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1

Actions of Melatonin, Its Structural and Functional Analogs in the Central Nervous System and the Significance of Metabolism

Hardeland, Rudiger, Poeggeler, Burkhard

Journal:

Central Nervous System Agents in Medicinal Chemistry(Formerly Current Medicinal Chemistry - Central Nervous System Agents)

Year:

2007

Language:

english

File:

PDF, 279 KB

english, 2007

2

Inconsistent suppression of nocturnal pineal melatonin synthesis and serum melatonin levels in rats exposed to pulsed DC magnetic fields

Russel J. Reiter, Dun Xian Tan, Burkhard Poeggeler, Robert Kavet

Journal:

Bioelectromagnetics

Year:

1998

Language:

english

File:

PDF, 215 KB

english, 1998

3

Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease

Etsuro Matsubara, Tara Bryant-Thomas, Javier Pacheco Quinto, Tracey L. Henry, Burkhard Poeggeler, Donald Herbert, Felix Cruz-Sanchez, Yau-Jan Chyan, Mark A. Smith, George Perry, Mikio Shoji, Koji Abe,

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 228 KB

english, 2003

4

Reduced oxidative damage in ALS by high-dose enteral melatonin treatment

Jochen H. Weishaupt, Claudia Bartels, Esther Pölking, Jeannine Dietrich, Gundula Rohde, Burkhard Poeggeler, Nina Mertens, Swetlana Sperling, Matthias Bohn, Gerald Hüther, Armin Schneider, Alfred Bach,

Journal:

Journal of Pineal Research

Year:

2006

Language:

english

File:

PDF, 450 KB

english, 2006

5

Melatonin As a Free Radical Scavenger: Implications for Aging and Age-Related Diseases

RUSSEL J. REITER, DUN-XIAN TAN, BURKHARD POEGGELER, ARMANDO MENENDEZ-PELAEZ, LI-DUN CHEN, SEPPO SAARELA

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 737 KB

english, 1994

6

Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence

Armando Menendez-Pelaez, Burkhard Poeggeler, Russel J. Reiter, Lornell Barlow-Walden, Marta I. Pablos, Dun-xian Tan

Journal:

Journal of Cellular Biochemistry

Year:

1993

Language:

english

File:

PDF, 913 KB

english, 1993

7

Red-light-induced suppression of melatonin synthesis is mediated by N-methyl-D-aspartate receptor activation in retinally normal and retinally degenerate rats

Burkhard H. Poeggeler, Lornell R. Barlow-Walden, Russel J. Reiter, Seppo Saarela, Armando Menendez-Pelaez, Ken Yaga, Lucien C. Manchester, Li-Dun Chen

Journal:

Developmental Neurobiology

Year:

1995

Language:

english

File:

PDF, 672 KB

english, 1995

8

Melatonin's unique radical scavenging properties – roles of its functional substituents as revealed by a comparison with its structural analogs

Burkhard Poeggeler, Sandra Thuermann, Andreas Dose, Markus Schoenke, Susanne Burkhardt, Rüdiger Hardeland

Journal:

Journal of Pineal Research

Year:

2002

Language:

english

File:

PDF, 359 KB

english, 2002

9

Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): high tolerability of daily oral melatonin administration in ALS patients

Sonja Jacob, Burkhard Poeggeler, Jochen H. Weishaupt, Anna-Leena Sirén, Rüdiger Hardeland, Mathias Bähr, Hannelore Ehrenreich

Journal:

Journal of Pineal Research

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

10

The neuroprotective activities of melatonin against the Alzheimer β-protein are not mediated by melatonin membrane receptors

Miguel A. Pappolla, Marcia J. Simovich, Tara Bryant-Thomas, Yau-Jan Chyan, Burkhard Poeggeler, Margarita Dubocovich, Roger Bick, George Perry, Felix Cruz-Sanchez, Mark A. Smith

Journal:

Journal of Pineal Research

Year:

2002

Language:

english

File:

PDF, 566 KB

english, 2002

11

Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical

Dun-xian Tan, Rüdiger Hardeland, Lucien C. Manchester, Burkhard Poeggeler, Silvia Lopez-Burillo, Juan C. Mayo, Rosa M. Sainz, Russel J. Reiter

Journal:

Journal of Pineal Research

Year:

2003

Language:

english

File:

PDF, 231 KB

english, 2003

12

Non-vertebrate melatonin

Rüdiger Hardeland, Burkhard Poeggeler

Journal:

Journal of Pineal Research

Year:

2003

Language:

english

File:

PDF, 398 KB

english, 2003

13

Oxidation of melatonin by carbonate radicals and chemiluminescence emitted during pyrrole ring cleavage

Rüdiger Hardeland, Burkhard Poeggeler, Robert Niebergall, Veronika Zelosko

Journal:

Journal of Pineal Research

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

14

Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease

Etsuro Matsubara, Tara Bryant-Thomas, Javier Pacheco, Tracey L. Henry, Burkhard Poeggeler, Donald Herbert, Felix Cruz-Sanchez, Yau-Jan Chyan, Mark A. Smith, George Perry, Daniel G. Chain, Eyal Neria,

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 32 KB

english, 2003

15

Toxicity of the quinalphos metabolite 2-hydroxyquinoxaline: Growth inhibition, induction of oxidative stress, and genotoxicity in test organisms

Sonja Riediger, Andreas Behrends, Björn Croll, Ignacio Vega-Naredo, Nils Hänig, Burkhard Poeggeler, Jutta Böker, Sascha Grube, Juliane Gipp, Ana Coto-Montes, Chandana Haldar, Rüdiger Hardeland

Journal:

Environmental Toxicology

Year:

2007

Language:

english

File:

PDF, 371 KB

english, 2007

16

Development of indole-3-propionic acid (OXIGON™) for alzheimer’s disease

Paul E. Bendheim, Burkhard Poeggeler, Eyal Neria, Vivi Ziv, Miguel A. Pappolla, Daniel G. Chain

Journal:

Journal of Molecular Neuroscience

Year:

2002

Language:

english

File:

PDF, 84 KB

english, 2002

17

Mitochondrial medicine: neuroprotection and life extension by the new amphiphilic nitrone LPBNAH acting as a highly potent antioxidant agent

Burkhard Poeggeler, Grégory Durand, Ange Polidori, Miguel A. Pappolla, Ignacio Vega-Naredo, Ana Coto-Montes, Jutta Böker, Rüdiger Hardeland, Bernard Pucci

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

18

Leptin and the skin: a new frontier

Burkhard Poeggeler, Carla Schulz, Miguel A. Pappolla, Enikő Bodó, Stephan Tiede, Hendrik Lehnert, Ralf Paus

Journal:

Experimental Dermatology

Year:

2010

Language:

english

File:

PDF, 462 KB

english, 2010

19

The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?

Nicolette Farman, Eve Maubec, Burkhard Poeggeler, Jennifer E. Klatte, Frederic Jaisser, Ralf Paus

Journal:

Experimental Dermatology

Year:

2010

Language:

english

File:

PDF, 433 KB

english, 2010

20

A simple assay for the study of human hair follicle damage induced by ionizing irradiation

Burkhard Poeggeler, Enikö Bodó, Roger Nadrowitz, Juergen Dunst, Ralf Paus

Journal:

Experimental Dermatology

Year:

2010

Language:

english

File:

PDF, 360 KB

english, 2010

21

In vivo and in vitro effects of the pineal gland and melatonin on [Ca2++ Mg2+]-dependent ATPase in cardiac sarcolemma

Li-Dun Chen, Dun-Xian Tan, Russel J. Reiter, Ken Yaga, Burkhard Poeggeler, Pramod Kumar, Lucien C. Manchester, James P. Chambers

Journal:

Journal of Pineal Research

Year:

1993

Language:

english

File:

PDF, 550 KB

english, 1993

22

Melatonin, hydroxyl radical-mediated oxidative damage, and aging: A hypothesis

Burkhard Poeggeler, Russel J. Reiter, Dun-Xian Tan, Li-Dun Chen, Lucien C. Manchester

Journal:

Journal of Pineal Research

Year:

1993

Language:

english

File:

PDF, 1.98 MB

english, 1993

23

A review of the evidence supporting melatonin's role as an antioxidant

Russel J. Reiter, Daniela Melchiorri, Ewa Sewerynek, Burkhard Poeggeler, Lorneli Barlow-Walden, Jihing Chuang, Genaro Gabriel Ortiz, Dario AcuñaCastroviejo

Journal:

Journal of Pineal Research

Year:

1995

Language:

english

File:

PDF, 1.10 MB

english, 1995

24

Inhibitory effect of melatonin on cataract formation in newborn rats: Evidence for an antioxidative role for melatonin

Mitsushi Abe, Russel J. Reiter, Paul B. Orhii, Masayuki Hara, Burkhard Poeggeler

Journal:

Journal of Pineal Research

Year:

1994

Language:

english

File:

PDF, 618 KB

english, 1994

25

Detection and quantification of melatonin in a dinoflagellate, Gonyaulax polyedra: Solutions to the problem of methoxyindole destruction in non-vertebrate material

Burkhard Poeggeler, Rüdiger Hardeland

Journal:

Journal of Pineal Research

Year:

1994

Language:

english

File:

PDF, 939 KB

english, 1994

26

Elevation of cyclic GMP levels in the rat pineal gland induced by nitric oxide

Juan M. Guerrero, Russel J. Reiter, Burkhard Poeggeler, Li-Dun Chen, Dun-Xian Tan

Journal:

Journal of Pineal Research

Year:

1994

Language:

english

File:

PDF, 492 KB

english, 1994

27

On the primary functions of melatonin in evolution: Mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals

Ruediger Hardeland, Ivonne Balzer, Burkhard Poeggeler, Birgit Fuhrberg, Higinio Una, Gudrun Behrmann, Rupert Wolf, Torsten J. Meyer, Russel J. Reiter

Journal:

Journal of Pineal Research

Year:

1995

Language:

english

File:

PDF, 727 KB

english, 1995

28

Twenty-four hour urinary excretion of 6-hydroxymelatonin sulfate in Down syndrome subjects

Russel J. Reiter, Lornell Barlow-Walden, Burkhard Poeggeler, Sherry M. Heiden, Robert J. Clayton

Journal:

Journal of Pineal Research

Year:

1996

Language:

english

File:

PDF, 579 KB

english, 1996

29

Melatonin reduces H2O2-induced lipid peroxidation in homogenates of different rat brain regions

Ewa Sewerynek, Daniela Melchiorri, Genaro G. Ortiz, Burkhard Poeggeler, Russel J. Reiter

Journal:

Journal of Pineal Research

Year:

1995

Language:

english

File:

PDF, 555 KB

english, 1995

30

Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin

Dun-Xian Tan, Lucien C. Manchester, Rosa M. Sainz, Juan C. Mayo, Josefa Leon, Ruediger Hardeland, Burkhard Poeggeler, Russel J. Reiter

Journal:

Journal of Pineal Research

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

31

Melatonin neutralizes neurotoxicity induced by quinolinic acid in brain tissue culture

Ignacio Vega-Naredo, Burkhard Poeggeler, Verónica Sierra-Sánchez, Beatriz Caballero, Cristina Tomás-Zapico, Oscar Álvarez-García, Delio Tolivia, María J. Rodríguez-Colunga, Ana Coto-Montes

Journal:

Journal of Pineal Research

Year:

2005

Language:

english

File:

PDF, 507 KB

english, 2005

32

Reactions of the melatonin metabolite AMK (N1-acetyl-5-methoxykynuramine) with reactive nitrogen species: Formation of novel compounds, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK

Anna L. Guenther, Sonja I. Schmidt, Hartmut Laatsch, Serge Fotso, Heiko Ness, Anna-Rebekka Ressmeyer, Burkhard Poeggeler, Rüdiger Hardeland

Journal:

Journal of Pineal Research

Year:

2005

Language:

english

File:

PDF, 360 KB

english, 2005

33

Interactions of melatonin and its metabolites with the ABTS cation radical: extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones

Joachim Rosen, Ni Ni Than, Dorothea Koch, Burkhard Poeggeler, Hartmut Laatsch, Rüdiger Hardeland

Journal:

Journal of Pineal Research

Year:

2006

Language:

english

File:

PDF, 578 KB

english, 2006

34

Suppressive effect of melatonin administration on ethanol-induced gastroduodenal injury in rats in vivo

Daniela Melchiorri, Ewa Sewerynek, Russel J Reiter, Genaro G Ortiz, Burkhard Poeggeler, Giuseppe Nisticò

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 358 KB

english, 1997

35

Melatonin, aging, and age-related diseases

Burkhard Poeggeler

Journal:

Endocrine (Springer)

Year:

2005

Language:

english

File:

PDF, 146 KB

english, 2005

36

Evaluation of the antioxidant activity of melatonin in vitro

Karyn-Ann Marshall, Rüssel J. Reiter, Burkhard Poeggeler, Okezie I. Aruoma, Barry Halliwell

Journal:

Free Radical Biology and Medicine

Year:

1996

Language:

english

File:

PDF, 659 KB

english, 1996

37

Systemic d-amphetamine administration causes a reduction of kynurenic acid levels in rat brain

Arash Rassoulpour, Hui-Qiu Wu, Burkhard Poeggeler, Robert Schwarcz

Journal:

Year:

1998

Language:

english

File:

PDF, 324 KB

english, 1998

38

Indole-3-propionate: a potent hydroxyl radical scavenger in rat brain

Burkhard Poeggeler, Miguel A. Pappolla, Rüdiger Hardeland, Arash Rassoulpour, Paul S. Hodgkins, Paolo Guidetti, Robert Schwarcz

Journal:

Year:

1999

Language:

english

File:

PDF, 106 KB

english, 1999

39

Neurotoxicity of Dextrorphan

Genaro G Ortiz, Juan M Guerrero, Russel J Reiter, Burkhard H Poeggeler, Oscar K Bitzer-Quintero, Alfredo Feria-Velasco

Journal:

Archives of Medical Research

Year:

1999

Language:

english

File:

PDF, 647 KB

english, 1999

40

Amphiphilic Amide Nitrones: A New Class of Protective Agents Acting as Modifiers of Mitochondrial Metabolism

Durand, Grégory, Poeggeler, Burkhard, Ortial, Stéphanie, Polidori, Ange, Villamena, Frederick A., Böker, Jutta, Hardeland, Rüdiger, Pappolla, Miguel A., Pucci, Bernard

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 952 KB

english, 2010

41

Effects of indirectly acting 5-HT receptor agonists on circulating melatonin levels in rats

Gerald Huether, Burkhard Poeggeler, Lothar Adler, Eckart Rüther

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 517 KB

english, 1993

42

Melatonin's inhibitory effect on growth of ME-180 human cervical cancer cells is not related to intracellular glutathione concentrations

Li-Dun Chen, Belinda Z. Leal, Russel J. Reiter, Mitsushi Abe, Ewa Sewerynek, Daniela Melchiorri, Martin L. Meltz, Burkhard Poeggeler

Journal:

Year:

1995

Language:

english

File:

PDF, 649 KB

english, 1995

43

H2O2 induced lipid peroxidation in rat brain homogenates is greatly reduced by melatonin

Ewa Sewerynek, Burkhard Poeggeler, Daniela Melchiorri, Russel J. Reiter

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 224 KB

english, 1995

44

Pathophysiology of depression: Role of sleep and the melatonergic system

Venkataramanujan Srinivasan, Seithikurippu R. Pandi-Perumal, Ilya Trakht, D.Warren Spence, Ruediger Hardeland, Burkhard Poeggeler, Daniel P. Cardinali

Journal:

Psychiatry Research

Year:

2009

Language:

english

File:

PDF, 519 KB

english, 2009

45

Melatonin reverses the pro-fibrillogenic activity of apolipoprotein E.

Miguel A. Pappolla, Burkhard Poeggeler, J.-Y. Chyan, Tara Bryant-Thomas, Leticia Miravalle

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 183 KB

english, 2000

46

Photocatalytic mechanisms of indoleamine destruction by the quinalphos metabolite 2-hydroxyquinoxaline: a study on melatonin and its precursors serotonin and N -acetylserotonin

Behrends, Andreas, Riediger, Sonja, Grube, Sascha, Poeggeler, Burkhard, Haldar, Chandana, Hardeland, Rüdiger

Journal:

Journal of Environmental Science and Health Part B

Year:

2007

Language:

english

File:

PDF, 882 KB

english, 2007

47

Effect of tryptophan administration on circulating melatonin levels in chicks and rats: Evidence for stimulation of melatonin synthesis and release in the gastrointestinal tract

Gerald Huether, Burkhard Poeggeler, Andreas Reimer, Annette George

Journal:

Year:

1992

Language:

english

File:

PDF, 538 KB

english, 1992

48

Melatonin—A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitro

BURKHARD POEGGELER, SEPPO SAARELA, RUSSEL J. REITER, DUN-XIAN TAN, LI-DUN CHEN, LUCIEN C. MANCHESTER, LORNELL R. BARLOW-WALDEN

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 97 KB

english, 1994

49

Circadian Rhythms, Oxidative Stress, and Antioxidative Defense Mechanisms

Hardeland, Rüdiger, Coto‐Montes, Ana, Poeggeler, Burkhard

Journal:

Chronobiology International

Year:

2003

Language:

english

File:

PDF, 447 KB

english, 2003

50

Melatonin and Melatonergic Drugs on Sleep: Possible Mechanisms of Action

Srinivasan, Venkataramanujan, Pandi-Perumal, Seithikurippu R., Trahkt, Ilya, Spence, D. Warren, Poeggeler, Burkhard, Hardeland, Ruediger, Cardinali, Daniel P.

Journal:

International Journal of Neuroscience

Year:

2009

Language:

english

File:

PDF, 266 KB

english, 2009

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